Overlook of Gold Nanoparticles and Other Metal Nanoparticles Containing Gold

Gold Nanoparticles

Nanoparticles have become important materials in modern technologies compared with their bulk analogues not only as a result of their excellent structural features but also as a result of their unusual functional attributes. Most of the bulk materials we use in everyday life such as steel or sand are composed of micrometer scale particles. The properties of a material are related to the bonding...

Gold(0) porphyrins on gold nanoparticles.

Ciprofloxacin-protected gold nanoparticles.

The antibacterial drug ciprofloxacin (cfH) has been used to protect gold nanoparticles of two different mean diameters, 4 and 20 nm. The protection is complete with about 65 and 585 cfH molecules covering 4 and 15 nm particles, respectively. The nature of binding has been investigated by several analytical techniques. The nitrogen atom of the NH moiety of piperazine group binds on the gold surf...

Paclitaxel-functionalized gold nanoparticles.

Here we describe the first example of 2 nm gold nanoparticles (Au NPs) covalently functionalized with a chemotherapeutic drug, paclitaxel. The synthetic strategy involves the attachment of a flexible hexaethylene glycol linker at the C-7 position of paclitaxel followed by coupling of the resulting linear analogue to phenol-terminated gold nanocrystals. The reaction proceeds under mild esterific...

Gold nanoparticles and airway hyperreactivity.

We were delighted to read the article in the European Respiratory Journal by HUSSAIN et al. [1] which demonstrated aggravation of pulmonary inflammation and airway hyperreactivity by gold (Au) nanoparticles (NPs) in a mouse model of chemical-induced asthma. Exposure of sensitised (but not unsensitised) mice to Au NPs was shown to result in increased airway resistance and reactivity to methachol...